Nemesis
Else clues• ___ of one's existence
• ... the ___ of my existence
• 'I will not be afraid of death and ___': 'Macbeth'
• Affliction
• Anathema
• Bad thing
• Bete noire
• Blight
• Bringer of ill
• Bugaboo
• Bugbear
• Canker
• Cause of destruction
• Cause of distress
• Cause of harm
• Cause of misery
• Cause of one's undoing
• Cause of ruin
• Cause of ruination
• Cause of woe
• Curse
• Deadly poison
• Dennis, to Mr. Wilson
• Destruction
• Downfall
• Flea, to Fido
• Garlic, to a vampire
• Ill bringer
• Killer dog's name in the Diane Whipple case
• Leading
• Nuisance
• Plague
• Poison
• Poisonous-plant suffix
• Problem source
• Proverbial thorn
• Reason for ruin
• Ruin
• Ruin to Keats
• Ruination
• Ruinous agent
• Scourge
• Something avoided
• Something terrible
• Source of aggravation
• Source of harm
• Source of misery
• Source of ruin
• Source of trouble
• Spoiler
• Sun, to Frosty
• The ___ of one's existence
• Thorn in one's side
• Thorn in the flesh
• Thorn in the side
• Undoing
• Unhappy influence
• Witch's brew
• Woe
• Something causes misery or death