IRKS

Gets on the nerves of

• (missing clue)

• Aggravates

• Angers

• Anno

• Becomes a bane to

• Bothers

• Bugs

• Chafes

• Disturbs

• Drives to distraction

• Exasperates

• Galls

• Gets annoying

• Gets on one's nerves

• Gets on the wrong side of

• Gets one's goat

• Gets to

• Gets under one's skin

• Gets under the skin of

• Grates on

• Irritates

• Is on the back of

• Is trying

• Is vexing

• Is vexing to

• Maddens

• Makes angry

• Makes see red

• Miffs

• Nettles

• Peeves

• Perturbs

• Piques

• Proves troublesome

• Puts out

• Raises ire

• Rankles

• Really bothers

• Really bugs

• Really gets to

• Riles

• Rubs the wrong way

• Ruffles

• Ruffles feathers

• Tees off

• Tick's off

• Tires out

• Upsets

• Vexes