IRK

Really get to

• Aggravate

• Anger

• Annoy

• Badger

• Be a pain

• Be a thorn in the side of

• Bother

• Bother a lot

• Bother the heck out of

• Bug

• Bug a bit

• Bug greatly

• Bug the hell out of

• Chafe

• Discommode

• Do some button-pushing, so to speak

• Drive bananas

• Drive to distraction

• Drive up the wall

• Drive up the wall, so to speak

• Exasperate

• Gall

• Get on one's nerves

• Get on the bad side of

• Get on the nerves of

• Get one's goat

• Get to

• Get under one's skin

• Get under the skin of

• Go against the grain

• Grate on

• Inflame

• Irritate

• It may be in front of some

• Make angry

• Make mad

• Make peeved

• Make upset

• Miff

• Needle

• Peeve

• Perturb

• Pester

• Pique

• Piss off

• Provoke

• Put in a pet

• Put out

• Raise one's hackles

• Rankle

• Rattle one's cage

• Really bug

• Really ruffle

• Rile

• Rile up

• Rub the wrong way

• Ruffle

• Ruffle feathers

• Ruffle the feathers of

• Run afoul of

• Set off

• Stick in one's craw

• Test the patience of

• Tick off

• Trouble

• Vex